Coagulation Profile in Dogs

Learn about coagulation profiles in dogs.

Coagulation is the process of forming a blood clot. It takes many steps that must all go right in the body. The coagulation process involves the following components:

Without proper coagulation, the dog has a bleeding disorder, which is dangerous and can even be life-threatening.

A coagulation profile is a set of blood tests that can help a veterinarian determine whether a dog that's bleeding abnormally has a coagulation problem and which stage in the process is not functioning correctly. That can aid in diagnosing the problem and choosing the proper treatment.

Coagulation Tests in Dogs Evaluate Coagulation Factors

Thirteen substances circulate in the bloodstream and work together in a specific sequence to trigger blood clotting when there is an injury. An intrinsic and extrinsic pathway are each triggered and, eventually, those two sequences come together in a final, common pathway.

In the lab, blood tests measure the functioning of the three pathways.

Coagulation Tests in Dogs

The following coagulation tests are part of a diagnostic evaluation:

Together with a CBC and basic blood chemistry results, a coagulation profile of PT, PTT, TT, and vWF can help a veterinarian determine which pathway of the coagulation system is malfunctioning. From there, further testing may be required to finish the diagnosis.

Interpretation of Coagulation Profile in Dogs

Interpreting the results of a coagulation profile is complicated and requires looking at all the test results together as well as keeping in mind physical exam and history results. A veterinarian uses a combination of results to develop a picture of what's going on inside the dog's body and reach a diagnosis and determine the best treatment course.

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